Madame Augustine’s House is part of the cathedral square. Dating from 1745 it is located on Calle Grande, in the historic centre. Madame Augustine became famous for her relationship with Frenchman Alejandro Prospero Reverand, Simon Bolivar’s doctor. So much so that during the carnivals of the time the chorus 'hawk tweet tweet, Reverend Monsieur Madame Augustine' was sung.